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Retinal and medical imaging

Completed2022–2025Aain-D

Aain-D: AI for diabetic retinopathy from retinal images

AI that grades diabetic retinopathy from retinal photographs, including a new Radon-transform method released as open-source software.

Project leadDr. Zubair Shah
5
Publications
3
Talks
3
Team members
0
Partners
Completed100%
20222025

Summary

We built AI that looks at photographs of the back of the eye and grades how far diabetic eye disease has progressed, so screening can reach more people.

Diabetic retinopathy is a leading cause of preventable vision loss, and early detection depends on regular retinal screening. Aain-D, funded by the HBKU Innovation Centre, set out to build an AI-enabled mobile tool to help diagnose diabetes and stratify diabetic retinopathy from retinal images.

The research introduced RadEx, a nonlinear Radon-inspired transform that turns retinal images into sinograms, and RadFuse, which combines these sinograms with fundus images in deep networks. Tested on the public APTOS-2019 and DDR datasets, the method achieved high grading accuracy and was released as open-source software.

Key findings

Quadratic kappa for five-class retinopathy grading with RadFuse, with 87% accuracy
0.932
Open-source Python package releasing the nonlinear Radon transform
RadEx
OverviewWhy it matters · Research question and aims · Impact

Why it matters

  • Diabetic retinopathy is a leading cause of preventable blindness, and early treatment works.
  • Screening depends on specialists reading many images. AI can help prioritise the people who need care first.

Research question and aims

The main research question
  1. Grade diabetic retinopathy severity from retinal fundus images.
  2. Develop new image-feature methods based on the Radon transform.
  3. Evaluate AI models for generating synthetic retinal images.
  4. Release the methods as reusable open-source software.

Impact

To be added

Who benefits and how: patients, clinicians, health services, policy, training (e.g. "Model shared with HMC diabetes clinic")

MethodsDesign, data and methods · Timeline and milestones · Ethics and data protection

Design, data and methods

Study design
Study design (e.g. prospective cohort, retrospective analysis, prototype evaluation)
Setting
Where the study takes place
Participants or sample
Who is included and how many

Analytics and AI methods

  • Deep learning
  • Radon and nonlinear Radon transforms
  • Multimodal fusion of images and sinograms

How the study works

  • Deep learning on retinal fundus images.
  • Linear and nonlinear Radon-transform sinograms as an additional input.
  • Comparative evaluation of generative models for retinal image synthesis.

Timeline and milestones

To be added

Milestones with dates (start, ethics approval, data collection, results, completion)

Ethics and data protection

Approving body
e.g. HBKU IRB, HMC MRC
Approval number
Approval or reference number
Data protection
How data are stored and protected
Team & partnersTeam · Partners and collaborators
OutputsOutputs

Outputs

Publications 5

Show these in the publications list

Talks

Software, datasets and tools

Keywords

  • Diabetic retinopathy
  • Medical imaging
  • Radon transform
  • Open-source software

Get involved

Use or extend our methods

RadEx is open-source. Contact us to collaborate on retinal AI or to test the methods on new data.

Contact us

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